Glycoproteins: glycan presentation and protein-fold stability
نویسندگان
چکیده
منابع مشابه
Glycan analysis of therapeutic glycoproteins
Therapeutic monoclonal antibodies (mAbs) are glycoproteins produced by living cell systems. The glycan moieties attached to the proteins can directly affect protein stability, bioactivity, and immunogenicity. Therefore, glycan variants of a glycoprotein product must be adequately analyzed and controlled to ensure product quality. However, the inherent complexity of protein glycosylation poses a...
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ژورنال
عنوان ژورنال: Structure
سال: 1999
ISSN: 0969-2126
DOI: 10.1016/s0969-2126(99)80095-1